Yes, there are several regulations and standards that govern the handling of flammable refrigerants. These include industry standards, such as IEC 60340-3-3 and ASHRAE 34, as well as national and international regulations, such as OSHA and EPA regulations in the United States. These regulations and standards provide guidelines for the safe handling, storage, and use of flammable refrigerants, including requirements for training, equipment, and emergency procedures. It is essential to familiarize yourself with the relevant regulations and standards to ensure compliance and minimize the risks associated with flammable refrigerants.