The type of refrigerant used affects piping design in terms of velocities and pressure drops. Different refrigerants have different thermodynamic properties, such as density, viscosity, and specific heat capacity, which impact the design of the piping system. For example, Refrigerant-22 (R-22) has a higher density and viscosity than Refrigerant-410A, which means that R-22 requires larger pipe sizes and more powerful pumps to achieve the same flow rate. Additionally, the pressure drop in the piping system will be different for different refrigerants, which affects the design of the condenser and evaporator coils.