The frequency of cleaning and inspecting drain lines and pans depends on various factors, including the type of HVAC system, usage, and environmental conditions. As a general rule, drain lines and pans should be inspected every 3-6 months, and cleaned annually or bi-annually. However, in areas with high humidity or heavy usage, more frequent cleaning and inspection may be necessary. It’s essential to consult the manufacturer’s recommendations and local regulations for specific guidance.