There are several emerging trends in refrigerant blend development for HVAC systems, including the development of low-GWP blends, natural refrigerant blends, and blends with improved thermodynamic efficiency. Additionally, researchers are exploring the use of new refrigerant components, such as hydrofluoroolefins (HFOs) and hydrocarbons, to create blends with enhanced performance and environmental characteristics. These trends are driven by the need to reduce the environmental impact of HVAC systems while maintaining or improving their performance.