The main difference between A2L and A3 flammable refrigerants lies in their flammability risk. A2L refrigerants have a lower flammability risk, with a burning velocity of ≤ 10 cm/s, whereas A3 refrigerants have a higher flammability risk, with a burning velocity of > 10 cm/s. This classification determines the level of safety measures and handling procedures required when working with these refrigerants. For instance, A3 refrigerants may require more stringent ventilation and explosion-proof equipment, while A2L refrigerants may be suitable for use in smaller, well-ventilated areas.