When selecting a refrigeration system for a commercial HVAC setup, there are several factors to consider. First, you should determine the size of the space you are cooling and the amount of cooling capacity you need. This will help you determine the type of refrigeration system that is best suited for your needs. Additionally, you should consider the energy efficiency of the system, as well as the cost of installation and maintenance. You should also consider the noise level of the system, as well as the availability of parts and service. Finally, you should consider the environmental impact of the system, as well as any local regulations that may apply. By taking all of these factors into account, you can ensure that you select the best refrigeration system for your commercial HVAC setup.