When handling flammable refrigerants, it is recommended to wear personal protective equipment (PPE) that includes flame-resistant clothing, gloves, safety glasses, and a face shield. This PPE can help protect against skin contact, eye irritation, and inhalation of refrigerant vapors. Additionally, PPE can also provide protection in the event of an explosion or fire. The specific type and level of PPE required will depend on the classification of the refrigerant and the tasks being performed.