In the event of a flammable refrigerant leak or spill, it is essential to follow established emergency procedures to minimize the risks of explosion, fire, or environmental harm. These procedures should include evacuation of the area, notification of authorities and emergency services, containment of the spill, and ventilation of the area. Personnel should be trained to respond to emergencies and should have access to the necessary equipment and resources, including spill response kits and fire extinguishers.