Designing an HVAC system with the right refrigeration for your home requires careful consideration of several factors. First, you must determine the size of the space you are cooling. This will help you determine the capacity of the refrigeration system you need. You should also consider the climate of the area you live in, as this will affect the type of refrigerant you should use. Additionally, you should consider the efficiency of the system, as this will help you save money in the long run. Finally, you should consider the installation process and the cost of the system, as this will help you make the best decision for your budget.